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Clinical Practice Guidelines For The Prevention, Diagnosis & Management of Infective Endocarditis

8 November 2017

Rationale And Process Of The Infective Endocarditis Guidelines Development


Infective endocarditis (IE) causes substantial morbidity and mortality despite advances in antimicrobial therapy, methods of diagnosis and treatment of complications.

This first edition clinical practice guidelines (CPG) has been developed to guide the prevention, diagnosis and management of IE for use by Malaysian healthcare professionals. The writing committee consisting of experts in infectious disease, cardiology, cardiothoracic surgery, microbiology, pharmacy and dentistry from the Ministry of Health, the National Heart Institute (IJN), the Ministry of Education hospitals and private healthcare has developed these guidelines using as references, best practice recommendations from internationally recognised bodies and latest available evidence-based articles. The CPG was developed based on the local landscape of IE and has been reviewed by a multidisciplinary team of experts involved in the comprehensive management of this disease.


To provide evidence-based guidance for the prevention, diagnosis and management of all patients with or at risk of IE with the aim to reduce related morbidity and mortality by:

• Facilitating the early diagnosis of IE, so appropriate treatment can be instituted early.
• Providing guidance on the principles of appropriate antimicrobial therapy based on the type of IE and the causative microorganisms.
• Determining the indications and optimal timing for cardiothoracic surgery in IE.
• Determining the indications for antimicrobial prophylaxis in the prevention of IE.

Please download the full document below...

  arrowCPG Management of Infective Endocarditis.pdf (English - pdf - 4117 Kb)   

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